Medea Botanicals
Giant horsetail / Cola de caballo

Giant horsetail / Cola de caballo

Equisetum giganteum

Photo credit: Frank Vincentz

Safety information

Safety information

Toxicity: Equisetum contains thiaminase, which breaks down thiamine (vitamin B1); chronic use risks thiamine deficiency (neurological/hepatic harm). Few in-vivo toxicity studies; no consensus non-toxic dose. Heat (~100 C), alcohol and alkaline processing inactivate thiaminase, so properly prepared teas/tinctures are preferred.

Contraindications: Pregnancy and lactation (insufficient data); thiamine deficiency or alcoholism (thiaminase risk); pre-existing electrolyte imbalance/heart or kidney disease (diuretic effect); avoid chronic/high-dose use.

Interactions: Additive fluid/electrolyte loss with diuretics; possible additive potassium loss; caution with lithium (diuretic-type herbs can raise lithium levels); may compound thiamine depletion with alcohol.

Pregnancy & breastfeeding: Pregnancy and lactation: insufficient data — avoid.

Evidence level

Preclinical

Supported by laboratory or animal studies; not yet confirmed in humans.

Preparations

infusion/tea, decoction, fluid extract/tincture (heat/alcohol preparation favored) · aerial stems

Part used: aerial stems

Traditional use: diuretic and for genitourinary disorders, kidney/bladder complaints, diarrhea, heartburn, inflammation

Proposed mechanism: chloroform extract showed diuretic activity in mice comparable to hydrochlorothiazide; high silica/minerals; thiaminase (B1 breakdown)

Dosage note (descriptive only): heat (~100 C), alcohol and alkaline processing inactivate thiaminase

Evidence:Preclinical

General preparation guide →

Associated conditions

Nutritional notes

High in silica and minerals but not used as a nutritional food; thiaminase makes raw chronic consumption unsafe.

Healing traditions

Sources (2)

  1. Horsetail, Drugs.com Natural Products monograph
  2. Phytochemistry and Pharmacology of the Genus Equisetum (Kidney Diseases), PMC7954623, 2021

All sources →

Sourcing & resources

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Not medical advice. Consult a qualified healthcare professional before using any plant or preparation.