Patha (velvet leaf / abuta)

Cissampelos pareira

Photo credit: Krish Dulal

Safety information

Toxicity: Caution. Hayatin (curare-type alkaloid) has neuromuscular-blocking activity; high doses hazardous. Traditional emmenagogue/abortifacient reputation.

Contraindications: Pregnancy — avoid (emmenagogue/abortifacient reputation); anesthesia/neuromuscular conditions (curare-type alkaloids).

Interactions: Neuromuscular blockers and anesthetics (additive — clinically significant), antimalarials; caution before surgery.

Pregnancy & breastfeeding: Avoid in pregnancy — emmenagogue/abortifacient reputation.

Evidence level

Preclinical

Supported by laboratory or animal studies; not yet confirmed in humans.

Preparations

powder · root

Part used: root

Evidence:Preclinical

in fever/diarrhea and gynecological formulas · root

Part used: root

Evidence:Preclinical

decoction · root

Part used: root

Traditional use: fever, diarrhea/dysentery, uterine disorders, antidote

Proposed mechanism: bisbenzylisoquinoline/tropoloisoquinoline alkaloids (hayatin, cissampareine, pareirine) — antipyretic, analgesic, antimalarial, antihaemorrhagic, curare-like neuromuscular-blocking

Evidence:Preclinical

General preparation guide →