Safety information
Safety information
Toxicity: Low orally at traditional doses; furanocoumarins are phototoxic (photosensitization, esp. with topical use + UV).
Contraindications: Yin-deficiency heat (TCM); photosensitivity caution.
Interactions: Furanocoumarins inhibit CYP3A4 (grapefruit-like) -> can raise levels of co-administered drugs; additive photosensitizers.
Evidence level
Supported by laboratory or animal studies; not yet confirmed in humans.
Preparations
powder (topical for sores) · root
Part used: root
in formula · root
Part used: root
decoction · root
Part used: root
Traditional use: releases the exterior, expels wind, opens the nose, dries dampness, relieves pain, expresses pus; frontal/supraorbital headache, sinus congestion, toothache, sores
Proposed mechanism: coumarins/furanocoumarins (imperatorin, isoimperatorin, byakangelicin), volatile oil — anti-inflammatory, analgesic, antimicrobial
Associated conditions
Nutritional notes
n/a
Healing traditions
Related plants
Sources (1)
- [E24] Angelica dahurica traditional uses/phytochemistry/pharmacology review
Sourcing & resources
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